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Vitamin E intake and systemic antioxidant status in competitive endurance horses

Published online by Cambridge University Press:  09 March 2007

CA Williams ,
DS Kronfeld ,
TM Hess ,
KE Saker ,
JE Waldron  and
PA Harris
CA Williams*
Affiliation:
Department of Animal and Poultry Science, Virginia Polytechnic Institute and State University, Blacksburg VA 24061, USA
TM Hess
Affiliation:
Department of Animal and Poultry Science, Virginia Polytechnic Institute and State University, Blacksburg VA 24061, USA
KE Saker
Affiliation:
Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg VA 24061, USA
JE Waldron
Affiliation:
Rectortown Equine Clinic, Rectortown VA 20118, USA
PA Harris
Affiliation:
Equine Studies Group, WALTHAM Centre for Pet Nutrition, Melton, Mowbray, UK
*
*Rutgers, The State University of New Jersey, Cook Campus, 84 Lipman Drive, New Brunswick, NJ 08901; Email: cwilliams@aesop.rutgers.edu
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Abstract

The objective was to compare vitamin E content in the total diet of Arabian horses competing in the 80 km Research Ride 2002 to the oxidative stress and antioxidant measures throughout the race. Prior to the race, riders completed a detailed nutritional survey, which was used to calculate vitamin E intake. Blood samples, temperature and heart rate were taken the day before the race, at 27 and 48 km during the race, at race completion or elimination and 3 h after race completion. Plasma lipid hydroperoxides, α-tocopherol (TOC), creatine kinase (CK), aspartate aminotransferase (AST), albumin, red and white blood cell total glutathione and glutathione peroxidase were measured. Data were analyzed by Pearson's correlation in SAS. From the survey, it was estimated that horses consumed 2265±114 IU day−1 of vitamin E. A negative correlation was found between the vitamin E intake and CK (r = −0.23; P = 0.002), and AST (r = −0.22; P = 0.003). A positive correlation was found between the vitamin E intake and plasma TOC (r = 0.15; P = 0.005) at all sample times. This suggests that intensely exercising horses supplemented with vitamin E may not have an improved welfare and performance if they are supplemented vitamin E versus what is naturally found in forages and commercial feeds.

Keywords

antioxidantsα-tocopherolenduranceequinemuscle enzymesnutritional survey
Type
Research Article
Information
Equine and Comparative Exercise Physiology , Volume 2 , Issue 3 , August 2005 , pp. 149 - 152
Copyright
Copyright © Cambridge University Press 2005

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References

1McBride, JM and Kraemer, WJ (1999). Free radicals, exercise and antioxidants. Journal of Strength and Conditioning Research 13: 175–183.Google Scholar
2McMeniman, NP and Hintz, HF (1992). Effect of vitamin E status on lipid peroxidation in exercised horses. Equine Veterinary Journal 24: 482–484.CrossRefGoogle ScholarPubMed
3National Research Council, (1989). Nutrient Requirements of Horses, 5th edn. Washington, DC: National Academy Press.Google Scholar
4Siciliano, PD, Parker, AL and Lawrence, LM (1996). Effect of dietary vitamin E supplementation on the integrity of skeletal muscle in exercised horses. Journal of Animal Science 75: 1553–1560.CrossRefGoogle Scholar
5Harris, PA (1998). Musculoskeletal disease. In: Reed, SM and Bayly, WM (eds), Equine Internal Medicine. London: W.B. Saunders Company, pp. 375–397.Google Scholar
6Williams, CA, Kronfeld, DS, Hess, TM, Saker, KE and Harris, PA (2004). Lipoic acid and vitamin E supplementation to horses diminishes endurance exercise induced oxidative stress, muscle enzyme leakage, and apoptosis. In: Lindner, A (ed.), The Elite Race and Endurance Horse. Oslo, Norway: CESMAS, pp. 105–119.Google Scholar
7Deaton, CM and Marlin, DJ (2005). Reactive oxygen species and antioxidants–a war of nutrition. The Veterinary Journal 169: 7–9.CrossRefGoogle Scholar
8de Moffarts, B, Kirschvink, N, Art, T, Pincemail, J and Lekeux, P (2005). Effect of oral antioxidant supplementation on blood antioxidant status in trained Thoroughbred horses. The Veterinary Journal 169: 65–74.CrossRefGoogle ScholarPubMed
9Mackay-Smith, M, Bentham, B, Cohen, M, Nelson, T, Ridgway, K and Steere, J (1999). Veterinary Guidelines for Judging AREC Endurance Competitions. Auburn, CA: The American Endurance Ride Conference, pp. 10–42.Google Scholar
10Williams, CA, Kronfeld, DS, Hess, TM, Waldron, JN, Crandell, KM, Saker, KE, Hoffman, RM and Harris, PA (2004). Antioxidant supplementation and subsequent oxidative stress of horses competing in a 80-km endurance race. Journal of Animal Science 82: 588–594.CrossRefGoogle Scholar
11Valberg, S, Jonsson, L, Lindholm, A and Holmgren, N (1993). Muscle histopathology and plasma aspartate aminotransferase, creatine kinase and myoglobin changes with exercise in horses with recurrent exertional rhabdomyolysis. Equine Veterinary Journal 25: 11–16.CrossRefGoogle ScholarPubMed
12Hargreaves, BJ, Kronfeld, DS, Holland, JL, Gay, LA, Cooper, WL, Sklan, DJ and Harris, PA (2001). Bioavailability and kinetics of natural and synthetic forms of vitamin E in Thoroughbred horses. Equine Nutrition and Physiology Symposium Proceedings 17: 127–128.Google Scholar
13Williams, CA, Kronfeld, DS, Hess, TM, Saker, KE, Waldron, JE, Crandell, KM and Harris, PA (2005). Comparison of oxidative stress and antioxidant status in endurance horses in three 80 km races. Equine and Comparative Exercise Physiology (in press).CrossRefGoogle Scholar
14Dysmsza, HA and Park, J (1975). Excess dietary vitamin E in rats. Federation of American Societies for Experimental Biology 34: 912.Google Scholar
15Abdo, KM, Rao, G and Montgomery, CA (1986). Thirteen-week toxicity study of d-α-tocopheryl acetate (vitamin E) in Fischer 344 rats. Food and Chemical Toxicology 24: 1043–1050.CrossRefGoogle ScholarPubMed
16Corrigan, JJ and Marcus, FI (1974). Coagulopathy association with vitamin E ingestion. Journal of the American Medical Association 230: 1300–1301.CrossRefGoogle ScholarPubMed
17Kusin, JA, Reddy, V and Sivakumar, B (1974). Vitamin E supplements and the absorption of a massive dose of vitamin E. American Journal of Clinical Nutrition 27: 774–776.CrossRefGoogle Scholar