British Journal of Nutrition

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Differences in postprandial inflammatory responses to a ‘modern’ v. traditional meat meal: a preliminary study

Fatemeh Aryaa1, Sam Eggera2, David Colquhouna3, David Sullivana4, Sebely Pala5 and Garry Eggera6 c1

a1 School of Human Nutrition, University of Sydney, Sydney, NSW, Australia

a2 Cancer Council NSW, Sydney, NSW, Australia

a3 University of Queensland, Brisbane, QLD, Australia

a4 Royal Prince Alfred Hospital, Sydney, NSW, Australia

a5 School of Public Health; ATN Centre for Metabolic Fitness, Curtin University, Perth, WA, Australia

a6 School of Health and Applied Sciences, Southern Cross University, Lismore, NSW, Australia

Abstract

A low-grade inflammatory response (‘metaflammation’) has been found to be associated with certain chronic diseases. Proposed inducers of this have been aspects of the modern lifestyle, including newly introduced foods. Plasma TAG, and the inflammatory cytokines C-reactive protein (CRP), TNF-α and IL-6 were compared in a randomised, cross-over trial using ten healthy subjects before and after eating 100 g of kangaroo, or a ‘new’ form of hybridised beef (wagyu) separated by about 1 week. Postprandial levels for 1 and 2 h of TAG, IL-6 and TNF-α were significantly higher after eating wagyu compared with kangaroo (P = 0·002 for TAG at 1 h, P < 0·001 at 2 h; P < 0·001 for IL-6 and TNF-α at 1 and 2 h). CRP was significantly higher 1 h postprandially after wagyu (P = 0·011) and non-significantly higher 2 h postprandially (P = 0·090). We conclude that the metaflammatory reaction to ingestion of a ‘new’ form of hybridised beef (wagyu) is indicative of a low-grade, systemic, immune reaction when compared with lean game meat (kangaroo). Further studies using isoenergetic intake and isolating fatty acid components of meats are proposed.

(Received November 02 2009)

(Revised March 01 2010)

(Accepted March 02 2010)

(Online publication April 09 2010)

Correspondence:

c1 Corresponding author: Dr Garry Egger, email eggergj@ozemail.com.au

Footnotes

Abbreviations: CRP, C-reactive protein