Epidemiology and Infection

Original Papers

Campylobacter infection

Risk factors for indigenous Campylobacter jejuni and Campylobacter coli infections in The Netherlands: a case-control study

Y. DOORDUYNa1 c1, W. E. VAN DEN BRANDHOFa1, Y. T. H. P. VAN DUYNHOVENa1, B. J. BREUKINKa1, J. A. WAGENAARa2a3a4 and W. VAN PELTa1

a1 Netherlands Centre for Infectious Disease Control, National Institute of Public Health and the Environment, Bilthoven, The Netherlands

a2 Central Veterinary Institute of Wageningen UR, Lelystad, The Netherlands

a3 Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands

a4 WHO Collaborating Center for Campylobacter/OIE Reference Laboratory for Campylobacteriosis

SUMMARY

A case-control study comprising 1315 Campylobacter jejuni cases, 121 Campylobacter coli cases and 3409 frequency-matched controls was conducted in The Netherlands in 2002–2003. Risk factors for both C. jejuni and C. coli enteritis were consumption of undercooked meat and barbecued meat, ownership of cats and use of proton pump inhibitors. Consumption of chicken was a predominant risk factor for C. jejuni enteritis, but many additional risk factors were identified. Unique risk factors for C. coli infections were consumption of game and tripe, and swimming. Contact with farm animals and persons with gastroenteritis were predominant risk factors for C. jejuni enteritis in young children (0–4 years). Important risk factors for the elderly (⩾60 years) were eating in a restaurant, use of proton pump inhibitors and having a chronic intestinal illness. Consumption of chicken in spring, steak tartare in autumn and winter and barbecued meat in rural areas showed strong associations with C. jejuni infections. This study illustrates that important differences in risk factors exist for different Campylobacter spp. and these may differ dependent on age, season or degree of urbanization.

(Accepted February 11 2010)

(Online publication March 12 2010)

Correspondence:

c1 Author for correspondence: Y. Doorduyn, M.Sc., Epidemiology and Surveillance Unit, Netherlands Centre for Infectious Disease Control, National Institute of Public Health and the Environment, PO Box 1, 3720 BA, Bilthoven, The Netherlands. (Email: yvonne.doorduyn@rivm.nl)

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