Behavioral and Brain Sciences

Open Peer Commentary

An agenda for symptom-based research

William Fleesona1, R. Michael Furra1 and Elizabeth Mayfield Arnolda1

a1 Department of Psychology, Wake Forest University, Winston-Salem, NC 27109.


The network approach proposed by Cramer et al. suggests fascinating new directions of research on mental disorders. Research is needed to find evidence for the causal power of symptoms, to examine symptoms thoroughly, to investigate individual differences in edge strength, to discover etiological processes for each symptom, and to determine whether and why symptoms cohere into distinct mental disorders.

Related Articles

  • Comorbidity: A network perspective