Epidemiology and Infection

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Epidemiology and Infection (2010), 138:1166-1171 Cambridge University Press
Copyright © Cambridge University Press 2009

Original Papers

Childhood infections

Aichi virus infection in children with acute gastroenteritis in Finland


a1 Vaccine Research Centre, University of Tampere Medical School, Tampere, Finland
a2 Department of Paediatrics, Tampere University Hospital, Tampere, Finland
a3 Institute of Medical Technology, University of Tampere, Finland
Article author query
kaikkonen s [PubMed]  [Google Scholar]
räsänen s [PubMed]  [Google Scholar]
rämet m [PubMed]  [Google Scholar]
vesikari t [PubMed]  [Google Scholar]


Aichi virus has been proposed as a novel causative agent of acute gastroenteritis. In addition to several Asian countries, South America and Africa, Aichi virus has also recently been found in Europe. Our objective was to study the causative role of Aichi virus in children with acute gastroenteritis in Finland. We analysed 595 stool specimens from infants in an efficacy trial of rotavirus vaccine and 468 stool specimens from children in a hospital-based epidemiological and aetiological study of acute gastroenteritis. The screening was done by nested reverse transcription–polymerase chain reaction amplifying a 519-bp segment and a 223-bp segment in the 3CD junction region of non-structural proteins. Aichi virus was detected in five stool samples (0·5%), of which four were co-infections with other gastroenteritis viruses. Two Aichi virus genotypes, A and B, were found. Aichi virus appears to be rare in children with acute gastroenteritis in Finland.

(Accepted November 04 2009)

(Online publication December 07 2009)

Key Words:Gastroenteritis; virology


c1 Author for correspondence: S. Kaikkonen, University of Tampere Medical School, Vaccine Research Centre, Biokatu 10, FIN-33520 Tampere, Finland. (Email: saija.kaikkonen@uta.fi)