Experimental Physiology



Research Article

Potassium channels in the human myometrium


Raheela N. Khan a1, Balwir Matharoo-Ball a1, Sabaratnam Arulkumaran a1 and Michael L. J. Ashford a2
a1 Academic Division of Obstetrics and Gynaecology, University of Nottingham, Derby City General Hospital, Uttoxeter New Road, Derby DE22 3NE and a2 Department of Biomedical Sciences, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK

Abstract

The contractility of the human uterus is under the fine control of a variety of interacting bioactive agents. During labour, the excitability of the uterus is drastically transformed in comparison with the non-labour state and is manifest at the membrane level via the acivity of uterine ion channels. This article reviews the contribution of potassium (K+) channels to human uterine excitability. Experimental Physiology (2001) 86.2, 255-264.