Public Health Nutrition

Assessment and methodology

Validation of nutrient intake using an FFQ and repeated 24 h recalls in black and white subjects of the Adventist Health Study-2 (AHS-2)

Karen Jaceldo-Siegla1a2 p1 c1, Synnove F Knutsena3, Joan Sabatéa1a2, W Lawrence Beesona1, Jacqueline Chana1, R Patti Herringa3, Terrence L Butlera1, Ella Haddada2, Hannelore Bennetta1, Susanne Montgomerya3, Shalini S Sharmaa1, Keiji Odaa1 and Gary E Frasera1

a1 Department of Epidemiology & Biostatistics, School of Public Health, Loma Linda University, Loma Linda, CA, USA

a2 Department of Nutrition, School of Public Health, Loma Linda University, Loma Linda, CA, USA

a3 Department of Health Promotion, School of Public Health, Loma Linda University, Loma Linda, CA, USA


Objective To validate a 204-item quantitative FFQ for measurement of nutrient intake in the Adventist Health Study-2 (AHS-2).

Design Calibration study participants were randomly selected from the AHS-2 cohort by church, and then subject-within-church. Each participant provided two sets of three weighted 24 h dietary recalls and a 204-item FFQ. Race-specific correlation coefficients (r), corrected for attenuation from within-person variation in the recalls, were calculated for selected energy-adjusted macro- and micronutrients.

Setting Adult members of the AHS-2 cohort geographically spread throughout the USA and Canada.

Subjects Calibration study participants included 461 blacks of American and Caribbean origin and 550 whites.

Results Calibration study subjects represented the total cohort very well with respect to demographic variables. Approximately 33 % were males. Whites were older, had higher education and lower BMI compared with blacks. Across fifty-one variables, average deattenuated energy-adjusted validity correlations were 0·60 in whites and 0·52 in blacks. Individual components of protein had validity ranging from 0·40 to 0·68 in blacks and from 0·63 to 0·85 in whites; for total fat and fatty acids, validity ranged from 0·43 to 0·75 in blacks and from 0·46 to 0·77 in whites. Of the eighteen micronutrients assessed, sixteen in blacks and sixteen in whites had deattenuated energy-adjusted correlations ≥0·4, averaging 0·60 and 0·53 in whites and blacks, respectively.

Conclusions With few exceptions validity coefficients were moderate to high for macronutrients, fatty acids, vitamins, minerals and fibre. We expect to successfully use these data for measurement error correction in analyses of diet and disease risk.

(Received June 15 2009)

(Accepted October 19 2009)

(Online publication December 08 2009)