Cardiology in the Young

Brief Reports

Magnetic resonance imaging findings in Loeys–Dietz syndrome

Israel Valverdea1a2 c1, John Simpsona2 and Philipp Beerbauma1a2

a1 King’s College London, Division of Imaging Sciences, London, United Kingdom

a2 Evelina Children’s Hospital, Guy’s & St Thomas Foundation Trust, Paediatric Cardiology, London, United Kingdom

Abstract

Loeys–Dietz syndrome is a newly described entity characterised by a constellation of arterial tortuosity, cranial malformations, and hypertelorism. We report a case of a 7-year old boy with confirmed Loeys–Dietz syndrome and discuss magnetic resonance imaging as a complete technique for assessment and follow-up of aggressive vascular pathology in the brain, thorax, and abdomen, which may dictate early surgical intervention.

(Received September 04 2009)

(Accepted October 18 2009)

(Online publication March 04 2010)

Correspondence:

c1 Correspondence to: Israel Valverde, King’s College London, Division of Imaging Sciences, The Rayne Institute, 4th Floor, Lambeth Wing St Thomas Hospital, London, SE1 7EH, United Kingdom. Tel: +44 (0) 2071888385; Fax: +44 (0) 2071885442; E-mail: isra.valverde@kcl.ac.uk