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Effect of Bromocryptine on hormones and milk secretion in Murrah buffaloes (Bubalus bubalis)

Published online by Cambridge University Press:  02 February 2010

J. Prasad  and
M. Singh
J. Prasad
Affiliation:
Defense Institute of Physiology and Allied Sciences (Defense Research and Development Organization), Timarpur, New Delhi, India
M. Singh*
Affiliation:
Dairy Cattle Physiology Division, National Dairy Research Institute, Karnal, Haryana, India
*
†E-mail: msingh8724@yahoo.co.in
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Abstract

An experiment was carried out on 10 advance pregnant Murrah buffaloes to determine the role of hormones in milk secretion around parturition. Experimental animals were administered with a single injection of bromocryptine, @ 100 μg/kg BW, for 5 days before expected calving, whereas control group buffaloes were injected with placebo injections. Blood samples collected before parturition (−5,−4,−3,−2,−1 days), on day of parturition (day-0) and on day 1, 2, 3, 4, 5, 10 and 15 post partum were analyzed for growth hormone (GH), insulin like growth factor-I (IGF-I) and prolactin (PRL) by radioimmunassay methods. Milk samples were collected daily for 5 days and on day 10 and 15 after parturition. Milk fat, protein, lactose, citric acid, non-esterified fatty acids (NEFAs) and somatic cell counts (SCCs) were determined in milk samples. Bromocryptine treatment significantly (P < 0.01) decreased pre partum PRL and increased GH levels (P < 0.01) on day of parturition in experimental buffaloes without influencing plasma IGF-I level. Milk yield was significantly lower (P < 0.01) in experimental than in control group. Further, effect of bromocryptine on milk yield was only for a week. Milk yield increased (P < 0.01) gradually and was similar to control group on day 15 post partum. Bromocryptine treatment significantly increased milk SCC (P < 0.01) and protein content (P < 0.01) but there was no effect of treatment on fat, lactose, citric acid, glucose, milk and plasma NEFA concentration. It was concluded that prepartum suppression of PRL by bromocryptine impairs milk secretion temporarily in ensuing lactation. The significant rise in GH level before parturition and on day of parturition suggests a role of it in milk secretion of buffaloes.

Keywords

bromocryptine, milk yield and composition, hormones, metabolites, buffaloes
Type
Full Paper
Information
animal , Volume 4 , Issue 5 , May 2010 , pp. 772 - 776
Copyright
Copyright © The Animal Consortium 2010

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