Journal of Hygiene

Research Article

The relationship between epidemic influenza A(H1N1) and ABO blood groups

M. Lebiusha1, L. Rannona2 and J. D. Karka3*

a1 Israel Defence Forces Medical Corps

a2 WHO National Influenza Center, Central Virological Laboratory, Ministry of Health, Israel

a3 Israel Defence Forces Medical Corps


An outbreak of influenza caused by the A(H1N1) subtype in military recruits in February 1978 afforded an opportunity to study the association of ABO blood groups with influenza morbidity and serological response. Fifty-eight per cent of 336 recruits became clinically ill. There was no differential distribution of clinical influenza by blood group. However, seroconversion to a titre of ≥ 20 was significantly and appreciably higher in groups A and B than O and AB. Also, among those with serologically confirmed clinical influenza, the occurrence was significantly higher in groups A and B than groups O and AB.

(Received October 01 1980)


* Requests for reprints should be addressed to Dr J. D. Kark, Department of Social Medicine, School of Public Health and Community Medicine, Faculty of Medicine, Ein Karem, Jersusalem, Israel.