Development and Psychopathology

Regular Articles

Developmental trajectories of restricted and repetitive behaviors and interests in children with autism spectrum disorders

Jennifer Richlera1 c1, Marisela Huertaa2, Somer L. Bishopa3 and Catherine Lorda4

a1 Indiana University

a2 University of Illinois–Chicago

a3 Cincinnati Children's Hospital Medical Center

a4 University of Michigan

Abstract

This study examined how restricted and repetitive behaviors and interests (RRBs) developed over time in a sample of children with autism spectrum disorders (ASD). One hundred ninety-two children referred for a diagnosis of autism at age 2, and 22 children with nonspectrum development disorders were evaluated with a battery of cognitive and diagnostic measures at age 2 and subsequently at ages 3, 5, and 9. Factor analysis of the RRB items on the Autism Diagnostic Interview–Revised revealed two RRB factors at each wave of data collection, one comprising “repetitive sensorimotor” (RSM) behaviors and the other “insistence on sameness” (IS) behaviors. For children with ASD, RSM scores remained relatively high over time, indicating consistent severity, whereas IS scores started low and increased over time, indicating worsening. Having a higher nonverbal intelligence (NVIQ) at age 2 was associated with milder concurrent RSM behaviors and with improvement in these behaviors over time. There was no relationship between NVIQ at age 2 and IS behaviors. However, milder social/communicative impairment, at age 2 was associated with more severe concurrent IS behaviors. Trajectory analysis revealed considerable heterogeneity in patterns of change over time for both kinds of behaviors. These findings are discussed in terms of their implications for our understanding of RRBs in ASD and other disorders, making prognoses about how RRBs will develop in children with ASD as they get older, and using RRBs to identify ASD phenotypes in genetic studies.

Correspondence

c1 Address correspondence and reprint requests to: Jennifer Richler, 1322 South Dunn Street, Bloomington, IN 47401; E-mail: jrichler@gmail.com.

Footnotes

This research was supported by grants from the National Institute of Mental Health (R01-MH066496) and the National Institute on Child Health and Human Development (U19-HD 35482) to Catherine Lord and from the National Institutes of Health (T32HD07489) to Len Abbeduto. We thank the faculty and staff at the University of Chicago, University of North Carolina, and University of Michigan who assisted in collecting and preparing the data reported in this article, as well as the children and families who participated in the various research projects. We also thank Kathy Welch and Noah Stoffman for providing statistical support.