Journal of the International Neuropsychological Society

Research Articles

Neuropsychological functioning as a predictor of employment activity in a longitudinal study of HIV-infected adults contemplating workforce reentry


a1 Department of Psychiatry and Biobehavioral Sciences, Cedars Sinai Medical Center, Los Angeles, California

a2 Department of Psychiatry, Harbor–University of California Los Angeles Medical Center, Torrance, California

a3 Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, California

a4 Department of Psychiatry, Los Angeles Biomedical Research Institute at Harbor–University of California Los Angeles Medical Center, Torrance, California

a5 The Neurobehavioral Group, Costa Mesa, California


Cognitive deficits are associated with HIV disease, and HIV-related cognitive deficits have been associated with declines in everyday functioning and vocational status. We administered a baseline neuropsychological (NP) test battery designed to assess estimated full-scale IQ, achievement, attention/concentration, executive function, language, mental speed, motor function, nonverbal memory, verbal memory, and visual-spatial function to a sample of 174 disabled, HIV-positive individuals enrolled in a randomized, controlled trial of a vocational-rehabilitation program. We then used these NP scores to predict employment at the end of participants’ study participation, using both hierarchical multiple regression and ordinal logistic regression models. The hierarchical multiple regression analyses did not predict participants’ employment activities at the end of study participation. In the ordinal logistic regression model, executive functioning weakly predicted employment status at the end of study participation and inspection of the predicted classifications revealed that 63% of the participants were incorrectly classified using this model. These results suggest that although predicting workforce reentry from NP testing may be statistically significant, NP testing may be of limited clinical value for informing the workforce reentry of disabled people with HIV who are interested in returning to work. (JINS, 2010, 16, 38–48.)

(Received February 08 2009)

(Reviewed July 22 2009)

(Accepted July 22 2009)


c1 Correspondence and reprint requests to: David J. Martin, Harbor–UCLA Medical Center, 1000 W. Carson Street, Box 488, Torrance, CA 90509. E-mail: