Behavioral and Brain Sciences

Open Peer Commentary

Models of neurological defects and defects in neurological models

Timothy Schallerta1

a1 Department of Psychology and Institute for Neuroscience, University of Texas at Austin, Austin, TX 78712.


The transition from research to patient following advances in transplantation research is likely to be disappointing unless it includes a better understanding of critically relevant characteristics of the neurological disorder and improvements in the animal models, particularly the behavioral features. The appropriateness of the model has less to do with the species than with how the species is used.