Behavioral and Brain Sciences

Open Peer Commentary

CNS transplant utility may surive even their hasty clinical application

Manuel Nieto-Sampedroa1

a1 Department of Neural Plasticity, Cajal Institute, 28002 Madrid, Spain


Neural cell transplants have been introduced in clinical practice during the last decade with mixed results, encouraged by success with simple animal models. This commentary is a reminder that although the ideas and techniques of transplantation appear simple, the variables involved in host-transplant integration still require further study. The field may benefit from a concerted, multidisciplinary approach.