Behavioral and Brain Sciences

Open Peer Commentary

Therapeutic neural transplantation: Boon or boondoggle?

John H. Haringa1

a1 Department of Anatomy and Neurobiology, St. Louis University School of Medicine, St. Louis, MO 63104


Despite reports of recovery of function after neural transplantation, the biological interactions between transplanted neurons and the host brain that are necessary to mediate recovery are unclear at present. One source of confusion is in the variety of models and protocols used in these studies. It is suggested that multisite experimentation using standard protocols, models, and recovery criteria would be helpful in moving neural transplantation from the laboratory to the clinic.