Behavioral and Brain Sciences

Open Peer Commentary

Building a rational foundation for neural transplantation

Hasker P. Davisa1 and Bruce T. Volpea2

a1 Department of Psychology, University of Colorado, Colorado Springs, CO 80933

a2 Department of Neurology and Neuroscience, Cornell University Medical College, Burke Institute for Medical Research, White Plains, NY 10605. hpdavis@colospgs.bitnet


The neural transplantation research described by Sinden and colleagues provides part of the rationale for the clinical application of neural transplantation. The authors are asked to clarify their view of the role of the cholinergic system in cognition, to address extrahippocampal damage caused by transient forebrain ischemia, and to consider the effects of delayed neural degeneration in their structure-function analysis.