Epidemiology and Infection



Incidence, seasonality and serotypes of rotavirus in Gipuzkoa (Basque Country), Spain. A 14-year study


G. CILLA a1, E. PÉREZ-TRALLERO a1a2c1, M. C. LÓPEZ-LOPATEGUI a1, A. GILSETAS a1 and M. GOMÁRIZ a1
a1 Servicio de Microbiología, Complejo Hospitalario Donostia, Aptdo de Correos 477, 20080 San Sebastián, Spain
a2 Departmento de Medicina Preventiva y Salud Pública, Universidad del País Vasco, San Sebastián, Spain

Abstract

Over a 14-year period (1984–97) the presence of rotavirus in stool samples from children under 15 years with acute gastroenteritis was studied by enzymoimmunoanalysis. Serotyping (G1–G4) was performed using monoclonal antibodies. A total of 17348 children under 15 were investigated. Rotavirus was detected in 3637 (21·0%) specimens, 74·6% of which were from children younger than 2 years old. G1 and G4 were the most frequent serotypes. In 1991–7, the minimum incidence of rotavirus gastroenteritis in children under 4 years of age was 21·7 cases/1000 children/year. By the age of 5 years, at least 1 out of 11·3 children and probably 1 out of every 5–6 children in this area had experienced an episode of rotavirus gastroenteritis that required medical care. In the 1984–90 period a clear seasonality was not observed but in the second period of the study (1991–7), seasonality was marked, with peak activity in winter.

(Accepted July 19 2000)


Correspondence:
c1 Author for correspondence.


Metrics