Aristotle (384–322 BC) was born in Stagira, Macedonia. He went to Athens and entered Plato's Academy when he was eighteen. He remained there until Plato's death in about 347 BC, when he left Athens to spend the next five years at Assos in Asia Minor and at Mytilene on the island of Lesbos, working on philosophy and biology. In 343 he was invited to return to Macedonia to tutor the son of Philip II of Macedonia, the future Alexander the Great. This lasted three or four years. After a further period at Stagira, Aristotle returned to Athens where he opened a philosophical school at the Lyceum or Peripatos. On the death of Alexander in 323 there was anti-Macedonian feeling in Athens, and to avoid the same fate as Socrates, Aristotle took refuge in Chalcis on the island of Euboea, leaving the school in the charge of his pupil Theophrastus. He died the following year.