The epidemiology of adenovirus infections in Greater Manchester, UK 1982–96
Data relating to 3313 adenovirus isolates from patients in Greater Manchester, UK between 1982 and 1996 were analysed using χ2 tests and 95% confidence intervals. Of the 3098 isolates that were typed, 18·6% were serotype 2, 14·9% serotype 3, 12·1% serotype 1 and 10·9% serotype 41. There was evidence of a seasonal occurrence of serotype 7 (March–August), serotype 2 (January–April), serotype 4 (June–August) and subgenus F (September–November). Children less than 5 years old were the most common group of patients with adenovirus infection (61·3%) compared to 24·2% for adults and only 5·6% for school children (5–15 years). Gastric symptoms were the most common amongst infants (47·6%) followed by respiratory (27·5%) and general symptoms (12·9%). In adults, the overwhelming clinical condition was conjunctivitis (88·9%). Despite the traditional association with adenoviruses, remarkably few cases of pharyngoconjunctival fever were recorded (1·7%).(Accepted May 24 2000)
c1 Author for correspondence: University Virology, 3rd Floor, Clinical Sciences Building, Central Manchester Healthcare Trust, Oxford Road, Manchester M13 9WL, UK.