Journal of Hygiene

Research Article

Plasmids in group JK coryneform bacteria isolated in a single hospital

S. M. Kerry-Williamsa1 p1 and W. C. Noblea1

a1 Department of Bacteriology, Institute of Dermatology, Homerton Grove, London E9 6BX

Abstract

Investigation of 39 JK-type coryneform isolates from patients at a single hospital revealed that 23 possessed plasmids, which formed six groups on restriction endonuclease analysis. Four of the groups were associated with production of similar bacteriocin-like substances, and shared a minimum of 6·4 kilobase pairs of DNA. These plasmids, found in isolates from different patients, provide strong direct evidence that person-to-person transmission of JK bacteria had occurred within the hospital.

(Received May 19 1986)

(Accepted June 06 1986)

Correspondence:

p1 Present address: Department of Microbiology, The Medical School, University of Bristol, Bristol BS8 1TD.

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