a1 Department of Bacteriology, Institute of Dermatology, Homerton Grove, London E9 6BX
Investigation of 39 JK-type coryneform isolates from patients at a single hospital revealed that 23 possessed plasmids, which formed six groups on restriction endonuclease analysis. Four of the groups were associated with production of similar bacteriocin-like substances, and shared a minimum of 6·4 kilobase pairs of DNA. These plasmids, found in isolates from different patients, provide strong direct evidence that person-to-person transmission of JK bacteria had occurred within the hospital.
(Received May 19 1986)
(Accepted June 06 1986)
p1 Present address: Department of Microbiology, The Medical School, University of Bristol, Bristol BS8 1TD.