Journal of Hygiene

Table of Contents - 1983 - Volume 91, Issue 01  

Research Article

Comparison of haemagglutination-inhibition and single radial haemolysis techniques for detecting antibodies to influenza A and B viruses

G. Mancinia1, I. Donatellia1, G. Arangio-Ruiza1, C. Rozeraa1 and T. Macchiaa2

a1 Departments of Virology, Istituto Superiore di Sanità – Viale Regina Elena 299, 00161 Rome, Italy

a2 Departments of Clinical Biochemistry, Istituto Superiore di Sanità – Viale Regina Elena 299, 00161 Rome, Italy

Abstract

The sensitivities of haemagglutination-inhibition (HI) and single radial haemolysis (SRH) techiques in detecting antibodies against influenza A/Bangkok/1/79, A/Brazil/11/78, B/Singapore/222/79, B/Hong Kong/5/72 strains, in human sera were compared. For antibodies to influenza B viruses the HI tests employing ether-treated antigens were also evaluated. The SRH technique appears to be more sensitive for detecting protective titres of antibodies against influenza B strains and influenza A/Brazil/11/78.

(Received October 26 1982)

(Accepted February 17 1983)

Metrics
Related Content