In this conversation, the world-renowned neurobiologist Yadin Dudai discusses the latest advances in memory research, specifically the discovery of memory ‘erasure’ associated with the inhibition of an enzyme called PKMzeta. The conversation tackles the reductionist method in scientific inquiry, the mind/brain dilemma, the problematics of animal models in memory research, and the therapeutic implications of this groundbreaking discovery.
KeywordsAnimal Models; Long-term Memory; Memory Erasers; Mind/Brain Dilemma; PKMzeta; PTSD; Reconsolidation; Reductionism
Joelle M. Abi-Rached is Research Officer of the ‘Brain, Self and Society’ project convened by Professor Nikolas Rose, and funded by the Economic and Social Research Council (Res 051-27-0194; http://www.lse.ac.uk/collections/brainSelfSociety/). She studied biology and medicine at the American University of Beirut, Lebanon, and holds an MSc in Philosophy and Public Policy from the LSE.
Yadin Dudai is the Sela Chair in Neurobiology and Head of the Department of Neurobiology at the Weizmann Institute of Science in Rehovot, Israel, and the Albert and Blanche Willner Family Global Distinguished Visiting Professor of Neural Science at New York University (NYU).