Behavioral and Brain Sciences

Open Peer Commentary

Praise for a critical perspective

David C. Airey a1 and Richard C. Shelton a1
a1 Department of Pharmacology, School of Medicine, Vanderbilt University, Nashville, TN 37232-8548.

Article author query
airey dc   [PubMed][Google Scholar] 
shelton rc   [PubMed][Google Scholar] 


The target article skillfully evaluates data on mental disorders in relation to predictions from evolutionary genetic theories of neutral evolution, balancing selection, and polygenic mutation-selection balance, resulting in a negative outlook for the likelihood of success finding genes for mental disorders. Nevertheless, new conceptualizations, methods, and continued interactions across disciplines provide hope.

(Published Online November 9 2006)