Epidemiology and Infection

Number of deaths among HIV-infected adults in France in 2000, three-source capture–recapture estimation

C. LEWDEN a1c1, E. JOUGLA a2, A. ALIOUM a3, G. PAVILLON a2, L. LIÈVRE a4, P. MORLAT a1a5, D. SALMON a6, T. MAY a7, G. CHÊNE a1, D. COSTAGLIOLA a3 and the Mortalité 2000 Study Group.
a1 INSERM U593, ISPED, Bordeaux, France
a2 INSERM CépiDc, Le Vésinet, France
a3 INSERM E0338, Bordeaux, France
a4 INSERM U720; Université Pierre et Marie Curie, Paris, France
a5 Service de Médecine interne, Hôpital St André, Bordeaux, France
a6 Service de Médecine interne, Hôpital Cochin-Tarnier, Paris, France
a7 Service des maladies infectieuses et tropicales, Hôpital Brabois, Vandoeuvre-Les-Nancy, France

Article author query
lewden c   [PubMed][Google Scholar] 
jougla e   [PubMed][Google Scholar] 
alioum a   [PubMed][Google Scholar] 
pavillon g   [PubMed][Google Scholar] 
lievre l   [PubMed][Google Scholar] 
morlat p   [PubMed][Google Scholar] 
salmon d   [PubMed][Google Scholar] 
may t   [PubMed][Google Scholar] 
chene g   [PubMed][Google Scholar] 
costagliola d   [PubMed][Google Scholar] 


We estimated the number of deaths in France for the year 2000 in HIV-infected adults using three sources. The sources were (1) the ‘Mortalité 2000’ survey (M2000): 964 deaths were documented by 185 hospital wards involved in HIV management; (2) 1288 death certificates with a mention of HIV infection (INSERM-CepiDc) and (3) the French hospital database on HIV infection (FHDH) identified 654 deaths. The capture–recapture method was used with log-linear modelling. Overall 1559 deaths were observed. Estimation of the number of deaths in France was 1699 (95% CI 1671–1727). The completeness of M2000, CepiDc and FHDH were 55%, 76% and 38% respectively. Diversification of diseases and of causes of death in HIV-infected adults may explain: (1) the diversification of physicians involved in their management and incomplete coverage of M2000 and FHDH, and (2) why HIV infection was not mentioned in all death certificates.

(Accepted March 8 2006)
(Published Online May 11 2006)

c1 ISPED-INSERM U593, 146 rue Léo-Saignat 33076 Bordeaux cedex, France. (Email: charlotte.lewden@isped.u-bordeaux2.fr)