Psychological Medicine

Research Article

Memory functions and prophylactic treatment with lithium

L. Smigana1 c1 and C. Perrisa1

a1 Department of Psychiatry, Umeå University, Umeå Sweden

Abstract

Memory functions were examined in a group of 53 patients with affective disorders before commencing prophylactic lithium therapy and then after 4 and 12 months of lithium treatment. The memory tests administered were the 30 Figure Test, the 30 Word-Pair Test, the 30 Person-Data Test (these tests are included in the Cronhoim–Molander test battery) and the 30 Face Test. Three scores were obtained: immediate memory score, delayed memory score and forgetting score. There were no statistical significant differences between these scores before lithium therapy or after 4 and 12 months, except for immediate and delayed memory on the Person-Data Test and the 30 Face Test which showed an increased score of memory functions. The results of this study support the view that long-term lithium treatment with serum levels of about 0·6 mmol/1 does not induce memory disturbances.

Correspondence:

c1 Address for correspondence: Dr Ludovit smigan, Department of Psychiatry, Umeå University, 901 85 Umeå, Sweden.

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