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Physiological and pharmacological basis for the chemotherapy of enuresis1

Published online by Cambridge University Press:  09 July 2009

J. D. Stephenson
J. D. Stephenson*
Affiliation:
Department of Pharmacology, Institute of Psychiatry, London
*
2Address for correspondence: Dr J. D. Stephenson, Department of Pharmacology, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF.
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Synopsis

Enuresis is a disorder of micturition occurring in the absence of an organic urinary tract lesion. To understand its possible causation, the mechanisms controlling micturition are described together with the possible sites of action of various anti-enuretic agents, particularly imipramine. It is concluded that further research into the central control of micturition is required before the precise actions of centrally-acting anti-enuretic agents can be elucidated. Knowledge of these may give insight into the nature of the defect causing enuresis.

Type
Research Article
Information
Psychological Medicine , Volume 9 , Issue 2 , May 1979 , pp. 249 - 263
Copyright
Copyright © Cambridge University Press 1979

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Footnotes

1

This article formed the basis of a lecture given at the Institute of Psychiatry, London, October 1977.

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