Psychological Medicine

Brief Communication

Depression following withdrawal from long-term benzodiazepine use: a report of four cases

Dele Olajidea1 and Malcolm Ladera1 c1

a1 Psychopharmacology Unit, Institute of Psychiatry, London


Depression following withdrawal from long- or short-term use of benzodiazepines is not uncommon, yet it is under-reported in the benzodiazepine withdrawal literature. Four cases of depressive illness supervening during benzodiazepine withdrawal are reported. Depression may, it is suggested, be an integral part of the benzodiazepine withdrawal syndrome.


c1 Address for correspondence: Professor Malcolm Lader, Department of Pharmacology, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF.