Psychological Medicine

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Psychological Medicine (1990), 20:77-87 Cambridge University Press
Copyright © Cambridge University Press 1990

Original Articles

Psychiatric morbidity in patients with Parkinson's disease

R. G. Browna1 c1 and B. MacCarthya1

a1 Medical Research Council Human Movement and Balance Unit, National Hospital, Queen Square, London and Academic Unit, St Bernard Wing, Ealing Hospital, Uxbridge Road, Southall, Middlesex
Article author query
brown rg [PubMed]  [Google Scholar]
maccarthy b [PubMed]  [Google Scholar]


Forty patients with Parkinson's disease underwent a detailed assessment of their psychiatric state using a standardized, semi-structured interview, the Present State Examination. Analysis of the interviews yielded a profile of depressive and neurotic syndromes. Comparing the results with population norms, however, revealed that the patients were distinguished only by high levels of depressed mood and loss of interest and poor concentration. In the majority of patients the range and severity of symptoms fell below the criteria for ‘caseness’. Only four patients could be allocated to an ICD-9 class, two to ‘ neurotic depression’, one to ‘ anxiety state’ and one to ‘ phobic state’. This rate was almost identical to that found in the general population. Broader indices of psychiatric morbidity were related to the patients' levels of disability and cognitive function.


c1 Address for correspondence: Dr R. G. Brown, MRC Human Movement and Balance Unit, National Hospital, Queen Square, London WCIN 3BG.