Psychological Medicine

Original Articles

Quantitative computed tomographic study in schizophrenia: cerebral density and ventricle measures

Alessandro Rossia1 c1, Paolo Strattaa1, Luigi D'Albenzioa1, Vittorio Di Michelea1, Antonio Serioa1, Luigi Giordanoa1, Concetta Petruzzia1 and Massimo Casacchiaa1

a1 Department of Clinical Psychiatry, S. M. Collemaggio Hospital, L'Aquila, and ‘Villa Serena’, Città S. Angelo (Pescara), Italy

Synopsis

Twenty-seven chronic schizophrenics and nineteen controls, all male, were evaluated by computed tomography (CT) scans. Lateral, third and fourth ventricles and cerebral density numbers were measured. In the schizophrenic patients there was a significant increase in third ventricle width. Ventricular Brain Ratio (VBR) and there were significantly higher densities of white matter in the right frontal and parietal region.

Correspondence:

c1 Address for correspondence: Dr Alessandro Rossi, Clinica Psichiatrica dell' Università di L'Aquila, c/o Ospedale S. Maria di Collemaggio, 67100 L'Aquila, Italy.

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