Journal of the International Neuropsychological Society



Neuropsychological performance of adults with attention deficit hyperactivity disorder (ADHD): Diagnostic classification estimates for measures of frontal lobe/executive functioning


DAVID W.  LOVEJOY a1a2c1, J.D.  BALL a3, MATTHEW  KEATS a3, MICHAEL L.  STUTTS a3, EDWARD H.  SPAIN a3, LOUIS  JANDA a4 and JENNIFER  JANUSZ a2
a1 Hartford Hospital and The Institute of Living
a2 The Virginia Consortium Program in Clinical Psychology
a3 Eastern Virginia Medical School
a4 Old Dominion University

Abstract

ADHD adults (N = 26) were compared to normal controls (N = 26) on 6 neuropsychological measures believed sensitive to frontal lobe–executive functioning. MANOVA analyses and subsequent univariate tests indicated that most of the neuropsychological measures discriminated between the two groups. To address clinical significance, diagnostic classification rates were also generated for each measure individually, and for the battery as a whole. Levels of positive predictive power (PPP) for each of the 6 measures (83–100%) indicated that abnormal scores on these tests were good predictors of ADHD. However, estimates of negative predictive power (NPP) suggested that normal scores poorly predicted the absence of ADHD. When classification rates were calculated for the overall battery classification accuracy improved substantially. Thus, neuropsychological tests can differentiate adults suffering from ADHD from adults without ADHD, while also providing good classification accuracy. Finally, the pattern of neurobehavioral impairments exemplified through the Summary Index scores was interpreted as consistent with conceptualizations of ADHD depicting mild neurologic dysfunction in networks associated with the frontal lobes. (JINS, 1999, 5, 222–233.)

(Received December 19 1997)
(Revised June 12 1998)
(Accepted June 22 1998)


Key Words: Adult ADHD; Neuropsychological tests; Frontal lobe; Executive functioning.

Correspondence:
c1 Reprint requests to: David W. Lovejoy, The Institute of Living, Butler Building, Department of Psychology, 400 Washington Street, Hartford, CT 06106. E-mail: dlovejo@harthosp.org


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