Hostname: page-component-8448b6f56d-c47g7 Total loading time: 0 Render date: 2024-04-23T19:48:25.592Z Has data issue: false hasContentIssue false

Severe giardiasis and cryptosporidiosis in Scotland, UK

Published online by Cambridge University Press:  15 May 2009

L. J. Robertson
Affiliation:
Scottish Parasite Diagnostic Laboratory, Department of Bacteriology, Stobhill NHS Trust, Glasgow G21 3UW, Scotland, UK and Division of Environmental Health, Department of Civil Engineering, University of Strathclyde, Glasgow Gl 1XQ, Scotland, UK
Rights & Permissions [Opens in a new window]

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Hospital discharge data from 1990–4 for 26 hospitals were used to estimate and compare the cost and describe the epidemiology of severe giardiasis and cryptosporidiosis in Scotland, UK. The incidence of severe cryptosporidiosis was almost double that of severe giardiasis and the median duration of hospitalization was longer for cryptosporidiosis than giardiasis. Impaired immunity was frequently listed as co-diagnosis with cryptosporidiosis and associated with extended hospitalization. Although both infections were associated with infants, the median age was lower for cryptosporidiosis (5 years compared with 30 years). Whereas hospitalization was not significantly longer for infants with cryptosporidiosis, hospitalization for this age group with giardiasis was longer (4 days compared with 3 days). Comparison with similar data for giardiasis from USA revealed various differences and similarities. These points are discussed in relation to the epidemiology of these infections and published data were used to estimate costs of hospitalization.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1996

References

1.Rendtorff, RC. The experimental transmission of Giardia lamblia among volunteer subjects. In: Jakubowski, W, Hoff, JC, eds. Waterborne transmission of giardiasis. U.S. Environmental Protection Agency. Office of Research and Development, Environmental Research Center, Cincinnati, Ohio 45268, USA, EPA-600/9–79–001. 1979; 6481.Google Scholar
2.Miller, RA, Brondson, MA, Morton, WR. Experimental cryptosporidiosis in a primate model. J Infect Dis 1990; 161: 312–5.CrossRefGoogle Scholar
3.Du Pont, HL, Chappell, CL, Sterling, CR, Okhuysen, PC, Rose, JB, Jakubowski, W. Infectivity of Cryptosporidium parvum for adult humans. N Engl J Med 1995; 332: 855–9.CrossRefGoogle Scholar
4.Jephcott, AE, Begg, TN, Baker, AI. Outbreak of giardiasis associated with mains water in United Kingdom. Lancet 1986; i: 370–2.Google Scholar
5.Ljungstrom, I, Castor, B. Immune response to Giardia lamblia in a water-borne outbreak of giardiasis in Sweden. J Med Microbiol 1992; 36: 347–52.CrossRefGoogle Scholar
6.Hayes, EB, Matte, TD, O'Brien, TR et al. , Large community outbreak of cryptosporidiosis due to contamination of a filtered public water supply. N Engl J Med 1989; 320: 1372–6.CrossRefGoogle ScholarPubMed
7.MacKenzie, WR, Hoxie, NJ, Proctor, ME et al. , A massive outbreak in Milwaukee of Cryptosporidium infection transmitted through the public water supply. N Engl J Med 1994; 331: 161–7.CrossRefGoogle Scholar
8.Danciger, M, Lopez, M. Numbers of Giardia in the feces of infected children. Am J Trop Med Hyg 1975; 24: 237–42.CrossRefGoogle ScholarPubMed
9.Lengerich, EJ, Addiss, DG, Juranek, DD. Severe giardiasis in the United States. Clin Infect Dis 1994; 18: 760–3.CrossRefGoogle ScholarPubMed
10.World Health Organisation. International classification of diseases. Manual of the international statistical classification of diseases, injury and causes of death. Geneva: World Health Organisation, 1977.Google Scholar
11.Information and Statistics Division. Scottish Health Service Costs. Year ended 31st 03 1994. National Health Service in Scotland, Information and Statistics Division, Trinity Park House, South Trinity Road, Edinburgh EH5 3SQ. 1995.Google Scholar
12.Campbell, D. Cryptosporidiosis in Scotland - 1994. SCIEH Weekly Report 1995; 29: 46.Google Scholar
13.Overturf, GD. Editorial response: endemic giardiasis in the United States - role of the day-care center. Clin Infect Dis 1994; 18: 764–5.CrossRefGoogle Scholar
14.Smith, HV, Robertson, LJ, Campbell, AT, Girdwood, RWA. Giardia and giardiasis: what's in a name. Microbiol Eur 1995; 3: 22–9.Google Scholar
15.Ungar, BLP. Cryptosporidiosis in humans (Homo sapiens). In: Dubey, JP, Speer, CA, Fayer, R, eds. Cryptosporidiosis of man and animals. Boca Raton: CRC Press, 1990; 5982.Google Scholar
16.Webster, ADB. Giardiasis and immunodeficiency diseases. Trans Royal Soc Trop Med Hyg 1980; 74: 440–8.CrossRefGoogle ScholarPubMed
17.Farthing, MJG. Giardiasis as a disease. In: Thompson, RCA, Reynoldson, JA, Lymberry, AJ, eds. Giardia: from molecules to disease. Wallingford, UK: CAB International, 1994; 1537.Google Scholar
18.Rabbani, GH, Islam, A. Giardiasis in humans: populations most at risk and prospects for control. In: Thompson, RCA, Reynoldson, JA, Lymberry, AJ, eds. Giardia: from molecules to disease. Wallingford, UK: CAB International, 1994; 217–49.Google Scholar
19.Udezulu, IA, Visvesvara, GA, Moss, DM, Leitch, GA. Isolation of Giardia lamblia (WB strain) clones with distinct surface protein and antigenic profiles and differing infectivity and virulence. Infect Immun 1992; 60: 2274–80.CrossRefGoogle ScholarPubMed
20. Anonymous. WHO/PAHO informal consultation on intestinal protozoal infections. WHO/CDS/IPI/92.2., 1992.Google Scholar