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Epidemiology of Pseudomonas aeruginosa keratitis in contact lens wearers

Published online by Cambridge University Press:  15 May 2009

F. Stapleton ,
J. K. G. Dart ,
D. V. Seal  and
M. Matheson
F. Stapleton*
Affiliation:
Department of Optometry and Visual Science, the City University, 311–321 Goswell Road, London EC1V 7DD Moorfields Eye Hospital, City Road, London Department of Clinical Ophthalmology, Institute of Ophthalmology, Moorfields Eye Hospital, City Road, London
J. K. G. Dart
Affiliation:
Moorfields Eye Hospital, City Road, London Department of Clinical Ophthalmology, Institute of Ophthalmology, Moorfields Eye Hospital, City Road, London
D. V. Seal
Affiliation:
Moorfields Eye Hospital, City Road, London Tennent Institute of Ophthalmology, Western Infirmary, 38 Church Street, Glasgow
M. Matheson
Affiliation:
Moorfields Eye Hospital, City Road, London Department of Clinical Ophthalmology, Institute of Ophthalmology, Moorfields Eye Hospital, City Road, London
*
* For correspondence.
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Summary

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This study evaluated the epidemiology of Pseudomonas aeruginosa keratitis in contact lens (CL) wearers; the relationships between CL storage case contamination and CL hygiene practice and between CL hygiene and the development of keratitis. Sixteen CL wearers with keratitis were compared with 44 asymptomatic controls. Lens hygiene practice was assessed and CL care materials, domestic water sites and endogenous sites were evaluated microbiologically. Poor CL hygiene was not associated with Ps. aeruginosa keratitis. There was an association between keratitis and bacterial contamination of the CL and storage case (P < 0·0005). Lens and storage case contamination were not significantly associated with poor hygiene. No domestic or endogenous source for Ps. aeruginosa was found. Causative organisms may be derived from other sources, but CLs and CL storage cases provide a favourable environment for Ps. aeruginosa colonization. Changing the CL care environment to one less favourable for Ps. aeruginosa may help to eliminate this problem.

Type
Research Article
Information
Epidemiology & Infection , Volume 114 , Issue 3 , June 1995 , pp. 395 - 402
Copyright
Copyright © Cambridge University Press 1995

References

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