Hostname: page-component-8448b6f56d-wq2xx Total loading time: 0 Render date: 2024-04-23T10:46:21.421Z Has data issue: false hasContentIssue false
  • English
  • Français

The use of saliva for viral diagnosis and screening.

Published online by Cambridge University Press:  15 May 2009

Philip P. Mortimer  and
John V. Parry
Philip P. Mortimer
Affiliation:
PHLS Virus References Laboratory, Colindale, London NW9 5HT
John V. Parry
Affiliation:
PHLS Virus References Laboratory, Colindale, London NW9 5HT
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The strength and diversity of antibody responses to infection are the basis for many of the most rapid and sensitive tests in virology, yet the need to obtain the patient's consent and co–operation, to collect blood from a vein and to separate the serum before the test often deters investigators, particularly if children are involved or if there is added risk, difficulty or cost in doing the venepuncture.

Type
Special Article
Information
Epidemiology & Infection , Volume 101 , Issue 2 , October 1988 , pp. 197 - 201
Copyright
Copyright © Cambridge University Press 1988

References

Brown, D. W. G. (1986). Viral diagnosis by antibody capture assay. In Public Health Virology–12 Reports (ed. Mortimer, P. P.), pp. 92–108.Google Scholar
Cohen, B. J., Mortimer, P. P. & Pereira, M. S. (1983). Diagnostic assays with monoclonal antibodies for the human serum parvovirus–like virus (SPLV). Journal of Hygiene (London) 91. 113–130.CrossRefGoogle ScholarPubMed
Duermeyer, W., Wieland, F. & Van Der, Veen J. (1979). A new principle for the detection of specific IgM antibodies as applied in an ELISA for hepatitis A. Journal of Medical Virology 4. 25–32.CrossRefGoogle Scholar
Flehmig, B., Ranke, M., Berthold, H. & Gerth, H. J. (1979). A solid phase radio–immunoassay for detection of IgM antibodies to hepatitis A virus. Journal of Infectious Diseases 140. 169–175.CrossRefGoogle Scholar
Golub, L. M. & Kleinberg, I. (1976). Gingival crevicular fluid: A new diagnostic aid in managing the periodontal patient. Oral Sciences Reviews (ed. Melcher, A.H.Zarib, G. A.), pp. 49–61.Google Scholar
Henle, G. & Henle, W. (1986). Epstein–Barr virus–specific IgA serum antibodies as an outstanding feature of nasopharyngeal carcinoma. International Journal of Cancer 17, 1–7.CrossRefGoogle Scholar
Jenkins, G. N. (1978). The Physiology and Biochemistry of the Mouth, 4th ed., pp. 324–327. Blackwell Scientific publications, Oxford.Google Scholar
Lehner, T. (1982). Immunological Aspects of Oral Disease: Clinical Aspects of Immunology, 4th ed. (ed. Lachman, and Peters, ), pp. 939–943. Oxford: Blackwell Scientific Publications.Google Scholar
Murray, P. A., Greive, W. G. & Winkler, J. R. (1987). The humoral immune response in HIV associated periodontitis Abstract (THP 142) presented at IIIrd International Conference on AIDS.Google Scholar
Parry, J. V. (1986). An immunoglobulin G capture assay (GACRIA) for anti–HTLV III/LAV and its use as a confirmatory test. Journal of Medical Virology 19, 387–397.CrossRefGoogle ScholarPubMed
Parry, J. V., Perry, K. R. & Mortimer, P. P. (1987). Sensitive assays for viral antibodies in saliva: an alternative to tests on serum. Lancet 72–75.CrossRefGoogle ScholarPubMed