Epidemiology and Infection



Continuing Mycobacterium bovis transmission from animals to humans in New Zealand


M. G. BAKER a1c1, L. D. LOPEZ a1, M. C. CANNON a2, G. W. DE LISLE a2 and D. M. COLLINS a2
a1 Institute of Environmental Science and Research Ltd (ESR), Porirua, New Zealand
a2 AgResearch, Wallaceville, Upper Hutt, New Zealand

Article author query
baker mg   [PubMed][Google Scholar] 
lopez ld   [PubMed][Google Scholar] 
cannon mc   [PubMed][Google Scholar] 
de lisle gw   [PubMed][Google Scholar] 
collins dm   [PubMed][Google Scholar] 

Abstract

New Zealand has a large reservoir of Mycobacterium bovis infection in wild and farmed animals. This study aimed to assess the extent of human infection with this organism and the potential contribution of these animal sources. Combined epidemiological and laboratory investigation of human tuberculosis cases over the period 1995–2002 showed that M. bovis accounted for 2·7% (54/1997) of laboratory-confirmed human tuberculosis cases, a rate of 0·2/100000 population. M. bovis isolates from humans (23) were typed using restriction endonuclease analysis (REA) and compared with isolates from wild and domestic animals (2600). Fourteen (61%) of the human isolates had REA patterns that were identical to patterns for isolates from cattle, deer, possums, ferrets, pigs, and occasionally cats. These results suggest a low level of ongoing M. bovis transmission from animal reservoirs to humans in New Zealand.

(Accepted December 10 2005)
(Published Online March 29 2006)


Correspondence:
c1 Department of Public Health, Wellington School of Medicine & Health Sciences, Box 7343, Wellington South, New Zealand. (Email: michael.baker@wnmeds.ac.nz)


Metrics