a1 Institute of Pharmacology, University of Milan, Medical School, Milan, Italy
The present experimental model offered the opportunity to study particular aspects concerning the avirulence stability of live streptomycin-dependent (Sm D) Salmonella vaccines, under conditions resembling human enteric fever. The results seem to indicate that, in practice, the risk of reversion to a virulent form during oral antityphoid vaccination with Sm D strains remains slight even after the interruption of concomitant streptomycin administration.
(Received February 12 1975)
p1 Present Address: Institute of Medical Microbiology, University of Geneva, 22, Quai E. Anserment, 1211 Geneva 4, Switzerland.