Cambridge Quarterly of Healthcare Ethics



SPECIAL SECTION: BIOETHICS AND WAR

Guidelines to Prevent Malevolent Use of Biomedical Research


SHANE K.  GREEN  a1 a2 , SARA  TAUB  a1 a3 , KARINE  MORIN  a1 a4 and DANIEL  HIGGINSON  a1 a4
a1 American Medical Association's Institute for Ethics and the Council on Ethical and Judicial Affairs of the American Medical Association
a2 American Medical Association's Institute for Ethics, the Council on Ethical and Judicial Affairs
a3 American Medical Association's Council on Ethical and Judicial Affairs
a4 Ethics Standards Group of the American Medical Association, and the Council on Ethical and Judicial Affairs

Article author query
green sk   [PubMed][Google Scholar] 
taub s   [PubMed][Google Scholar] 
morin k   [PubMed][Google Scholar] 
higginson d   [PubMed][Google Scholar] 

In February 1975, a group of leading scientists, physicians, and policymakers convened at Asilomar, California, to consider the safety of proceeding with recombinant DNA research. The excitement generated by the promise of this new technology was counterbalanced by concerns regarding dangers that might arise from it, including the potential for accidental release of genetically modified organisms into the environment. Guidelines developed at the conference to direct future research endeavors had several consequences. They permitted research to resume, bringing to an end the voluntary moratorium that the National Academy of Sciences (NAS) had instituted several months earlier. They also served to illustrate that the scientific community was capable of self-governance, thereby securing public trust and persuading Congress not to institute legislative restrictions. Finally, they underscored the importance of weighing unforeseen risks inherent in some research against potential benefits that may arise from these same endeavors. a



Footnotes

a The Council on Ethical and Judicial Affairs of the American Medical Association (AMA) formulates ethical policies for the medical profession through its interpretations of the AMA's Principles of Medical Ethics. The Council at the time this report was adopted consisted of Michael S. Goldrich, M.D. (Chair); Priscilla Ray, M.D. (Vice-Chair); Regina M. Benjamin, M.D., M.B.A.; Daniel Higginson (student member); Mark A. Levine, M.D.; John M. O'Bannon III, M.D.; Robert M. Sade, M.D.; Monique A. Spillman, M.D., Ph.D. (resident member); and Dudley M. Stewart, Jr., M.D. Staff to the Council at the time the report was adopted were Audiey Kao, M.D., Ph.D. (Vice President, Ethics Standards Group); Karine Morin, L.L.M. (Secretary); and Sara Taub, M.Be. Shane K. Green, Ph.D., was a Fellow in the AMA's Institute for Ethics.



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