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Antiseptic-impregnated central venous catheters reduce the incidence of bacterial colonization and associated infection in immunocompromised transplant patients

Published online by Cambridge University Press:  16 August 2006

S. J. George
Affiliation:
Department of Anaesthesia, St George's Hospital, London and Harefield Hospital, Middlesex, UK
P. Vuddamalay
Affiliation:
Department of Anaesthesia, St George's Hospital, London and Harefield Hospital, Middlesex, UK
M. J. Boscoe
Affiliation:
Department of Anaesthesia, St George's Hospital, London and Harefield Hospital, Middlesex, UK
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Abstract

The incidence of bacterial colonization of central venous catheters using a standard polyurethane catheter was compared with that using an antiseptic (silver sulphadiazine and chlorhexidine) impregnated catheter in a group of patients with thoracic organ transplantation. Colonization was reduced from 25 of 35 standard catheters to 10 of 44 study catheters (P < 0.002), a 68 % reduction. Similarly, the incidence of concomitant infection, by the same organism at another site was reduced from 10 of 35 standard catheters to 4 of 44 study catheters (P < 0.03), a 63% reduction.

Type
Original Article
Copyright
1997 European Society of Anaesthesiology

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