European Journal of Anaesthesiology

Original Article
(RD) Surgery

Antiseptic-impregnated central venous catheters reduce the incidence of bacterial colonization and associated infection in immunocompromised transplant patients

S. J. George a1c1, P. Vuddamalay a1 and M. J. Boscoe a1
a1 Department of Anaesthesia, St George's Hospital, London and Harefield Hospital, Middlesex, UK

Article author query
george sj   [PubMed][Google Scholar] 
vuddamalay p   [PubMed][Google Scholar] 
boscoe mj   [PubMed][Google Scholar] 


The incidence of bacterial colonization of central venous catheters using a standard polyurethane catheter was compared with that using an antiseptic (silver sulphadiazine and chlorhexidine) impregnated catheter in a group of patients with thoracic organ transplantation. Colonization was reduced from 25 of 35 standard catheters to 10 of 44 study catheters (P < 0.002), a 68 % reduction. Similarly, the incidence of concomitant infection, by the same organism at another site was reduced from 10 of 35 standard catheters to 4 of 44 study catheters (P < 0.03), a 63% reduction.

(Published Online August 16 2006)
(Accepted January 1997)

Key Words: central venous catheters; infection; transplantation.

c1 Correspondence: Dr S. J. George, Department of Anaesthesia, St George's Hospital, Blackshaw Road, Tooting, London SW19, UK.