The Journal of Laryngology & Otology



Clinical Records

Sinonasal inverted papilloma with malignant transformation in the middle ear: a multicentric origin?


Mazlina a1c1 , M A R Megat Shiraz a1 , M Y S Hazim a1 , A R Amran a2 , A N Zulkarnaen a3 and W M Wan Muhaizan a3
a1 Department of Otorhinolaryngology – Head & Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
a2 Department of Radiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia
a3 Department of Pathology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia

Article author query
mazlina s   [PubMed][Google Scholar] 
shiraz ma   [PubMed][Google Scholar] 
hazim my   [PubMed][Google Scholar] 
amran ar   [PubMed][Google Scholar] 
zulkarnaen an   [PubMed][Google Scholar] 
muhaizan wm   [PubMed][Google Scholar] 

Abstract

Inverted papilloma is a rare, benign tumour representing only 0.5 to 4 per cent of all sinonasal neoplasms; its involvement of the middle ear is extremely rare. We present a case of multicentric inverted papilloma in the sinonasal region and middle ear in a 54-year-old man. The patient later developed neck metastasis secondary to malignant transformation of the inverted papilloma in the middle ear.

(Published Online May 4 2006)
(Accepted November 30 2005)


Key Words: Papilloma, Inverted; Paranasal Sinuses; Ear, Middle; Epithelial Neoplasms, Malignant.

Correspondence:
c1 Address for correspondence: Dr Mazlina Bt Selamat, Department of Otorhinolaryngology – Head & Neck Surgery, Faculty of Medicine, UKM Hospital, Jalan Yaacob Latif, 56000 Kuala Lumpur, Malaysia. Fax: +603 91737840 E-mail: mazlinaselamat@yahoo.com