International Journal of Technology Assessment in Health Care


Priority setting for research in health care: An application of value of information analysis to glycoprotein IIb/IIIa antagonists in non-ST elevation acute coronary syndrome

Zoë Philips a1, Karl Philip Claxton a2, Stephen Palmer a2, Laura Bojke a2 and Mark John Sculpher a2
a1 University of Nottingham
a2 University of York


Abstract: The purpose of this study is to explain the rationale for the value of information approach to priority setting for research and to describe the methods intuitively for those familiar with basic decision analytical modeling. A policy-relevant case study is used to show the feasibility of the method and to illustrate the type of output that is generated and how these might be used to frame research recommendations. The case study relates to the use of glycoprotein IIb/IIIa antagonists for the treatment of patients with non-ST elevation acute coronary syndrome. This is an area that recently has been appraised by the National Institute for Health and Clinical Excellence.

Key Words: Priority setting; Value of information; Glycoprotein IIb/IIIa antagonists.