International Psychogeriatrics

Case Reports

Use of aripiprazole for psychosis and agitation in dementia

Jerson Laks a1c1, Roberto Miotto a2, Valeska Marinho a1 and Eliasz Engelhardt a3
a1 Center for Alzheimer's Disease and Related Disorders, Institute of Psychiatry, Federal University of Rio de Janeiro, RJ, Brazil
a2 Integrated Unit of Mental Health, Navy of Brazil, Brazil
a3 Section of Cognitive and Behavioral Neurology, Institute of Neurology, Federal University of Rio de Janeiro, RJ, Brazil

Article author query
laks j   [PubMed][Google Scholar] 
miotto r   [PubMed][Google Scholar] 
marinho v   [PubMed][Google Scholar] 
engelhardt e   [PubMed][Google Scholar] 


We report the case of an elderly woman with Alzheimer's disease, risk factors for vascular dementia, and atrium-ventricular blockade, who presented with severe agitation and psychosis. She was treated with aripiprazole and assessed with the Neuropsychiatric Inventory (NPI) over the course of 14 weeks. NPI scores showed a marked decrease in psychosis and agitation at week 4, and complete recovery at week 14, except for depression.

(Received February 24 2005)
(returned for revision April 28 2005)
(revised version received June 27 2005)
(Accepted June 30 2005)
(Published Online October 28 2005)

c1 Correspondence should be addressed to: Jerson Laks, Av Nossa Senhora de Copacabana 749/802, Rio de Janeiro, RJ, Brazil 22050-000. Phone: +55 21 2275 1122; Fax: +55 21 2548 4510. Email: