International Journal of Technology Assessment in Health Care

Special Section: The Quality of the Medical Evidence: Is It Good Enough?

Influences on the Quality of Published Drug Studies

Lisa A. Beroa1 and Drummond Renniea1

a1 University of California, San Francisco


To practice evidence-based medicine, physicians need data on the clinical effectiveness, toxicity, convenience, and cost of new drugs compared with available alternatives. We give examples of published drug studies that are defective, sometimes because pharmaceutical industry funding has affected their content and quality. We make recommendations on how to avoid these defects.