Quarterly Reviews of Biophysics

Research Article

Molecular Tuning of Ion Binding to Calcium Signaling Proteins

Joseph J. Falke, Steven K. Drake, Andrea L. Hazard and Olve B. Peersena1 c1

a1 Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309–0215

Intracellular calcium plays an essential role in the transduction of most hormonal, neuronal, visual, and muscle stimuli. (Recent reviews include Putney, 1993; Berridge, 1993a,b; Tsunoda, 1993; Gnegy, 1993; Bachs et al. 1992; Hanson & Schulman, 1992; Villereal & Byron, 1992; Premack & Gardner, 1992; Means et al. 1991).


c1 To whom correspondence should be addressed.