The Journal of Laryngology & Otology



Clinical Records

Benign mucous membrane pemphigoid of the upper aero-digestive tract: rare paraneoplastic syndrome presentation in renal cell carcinoma


Saravanan a1c1 , S T Baer a1 , Meredith a1 , Dyson a2 and Jan von der Werth a3
a1 Department of ENT, Conquest Hospital, Hastings, UK
a2 Department of Medicine, Conquest Hospital, Hastings, UK
a3 Department of Dermatology, Conquest Hospital, Hastings, UK

Article author query
saravanan k   [PubMed][Google Scholar] 
baer st   [PubMed][Google Scholar] 
meredith a   [PubMed][Google Scholar] 
dyson a   [PubMed][Google Scholar] 
werth jv   [PubMed][Google Scholar] 

Abstract

Benign mucous membrane pemphigoid is a rare autoimmune disorder affecting the upper aero-digestive tract and conjunctivae. This is a case presentation of benign mucous membrane pemphigoid affecting the oral mucosa, pharynx, oesophagus and larynx, leading to cicatricial lesions in the pharynx and larynx, causing dysphagia, hoarseness and stridor. The alternative forms of management for laryngeal scarring due to this disease are explained. The patient was later diagnosed with advanced renal cell carcinoma, raising the possibility of cicatricial pemphigoid manifesting as a paraneoplastic syndrome of underlying renal cell carcinoma.

(Accepted August 1 2005)


Key Words: Benign Mucous Membrane Pemphigoid; Paraneoplastic Syndromes; Renal Carcinoma; Airway Obstruction.

Correspondence:
c1 Address for correspondence: Mr K Saravanan, 21 The Turnpike, Fulwood, Preston, Lancashire PR2 3NT, UK. E-mail: saravanan1972@msn.com


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