Behavioral and Brain Sciences

Open Peer Commentary

The key role of prefrontal cortex structure and function

Antonino Raffone a1 and Gary L. Brase a2
a1 Division of Psychology, St. Peter's Campus, University of Sunderland, Sunderland, SR6 0DD, United Kingdom.
a2 Department of Psychological Sciences, University of Missouri-Columbia, Columbia, MO 65211.

Article author query
raffone a   [PubMed][Google Scholar] 
brase gl   [PubMed][Google Scholar] 


The tension between focusing on species similarities versus species differences (phylogenetic versus adaptationist approaches) recurs in discussions about the nature of neural connectivity and organization following brain expansion. Whereas Striedter suggests a primary role for response inhibition, other possibilities include dense recurrent connectivity loops. Computer simulations and brain imaging technologies are crucial in better understanding actual neuronal connectivity patterns.