Epidemiology and Infection



Short Report

Association of Mycobacterium tuberculosis Beijing genotype with tuberculosis relapse in Singapore


Y.-J. SUN a1c1, A. S. G. LEE a2, S.-Y. WONG a1 and N. I. PATON a1
a1 Department of Infectious Diseases, Tan Tock Seng Hospital,Singapore
a2 Division of Medical Sciences, National Cancer Centre, Singapore

Article author query
sun yj   [PubMed][Google Scholar] 
lee as   [PubMed][Google Scholar] 
wong sy   [PubMed][Google Scholar] 
paton ni   [PubMed][Google Scholar] 

Abstract

The relationship of Mycobacterium tuberculosis Beijing genotype with tuberculosis relapse was examined. Beijing strains were detected from 32 out of 45 (71%) relapsed cases and 148 out of 290 (51%) non-relapsed cases. Multivariate logistic regression analysis revealed that Beijing genotype was significantly associated with tuberculosis relapse (OR 2·64, 95% CI 1·30–5·34, P=0·005).

(Published Online October 5 2005)
(Accepted July 21 2005)
(October 5 2005)


Correspondence:
c1 Infectious Disease Research Laboratory, Level 2, TTSH Medical Centre, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433. (Email: Yong_Jiang_Sun@ttsh.com.sg)


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