The Journal of Laryngology & Otology

Table of Contents - 2003 - Volume 117, Issue 02  



(RF) Otorhinolaryngology

Bilateral parotid and submandibular gland enlargement: rare features of Wegener’s granulomatosis

S. Y. Liu F.R.C.S. (Ed.) , A. C. Vlantis F.C.S. (SA), Orl and W. C. Lee F.R.C.S.
a1 Division of Otorhinolaryngology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China

Article author query
liu sy   [PubMed][Google Scholar] 
vlantis ac   [PubMed][Google Scholar] 
lee wc   [PubMed][Google Scholar] 

Abstract

Wegener’s granulomatosis is a potentially fatal disease of unknown origin affecting mainly the upper and lower respiratory tracts and kidneys. Prompt recognition of the more unusual presentations of the disease is necessary to ensure early treatment. We present a case of a 46-year-old female with bilateral submandibular and parotid gland enlargement.

Parotid or submandibular salivary gland enlargement is a rare presenting feature of Wegener’s granulomatosis. Common to 80 per cent of these cases is nasal involvement, while ear pathology or lung lesions may occur in the remaining cases. The diagnosis is both clinical and pathological, biopsy of suspicious tissue, serum c-ANCA levels and a chest X-ray are valuable investigations. Treatment with immunosuppressive therapy is essential, and usually ensures a long-term remission.


Key Words: Salivary Gland Diseases; Parotid Gland; Submandibular Gland; Wegener’s Granulomatosis.

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