Epidemiology and Infection



Molecular fingerprinting defines a strain of Salmonella enterica serotype Anatum responsible for an international outbreak associated with formula-dried milk


E. J. THRELFALL a1c1, L. R. WARD a1, M. D. HAMPTON a1, A. M. RIDLEY a1, B. ROWE a1, D. ROBERTS a2, R. J. GILBERT a2, P. VAN SOMEREN a3, P. G. WALL a3p1 and P. GRIMONT a4
a1 Laboratory of Enteric Pathogens, Central Public Health Laboratory, 61 Colindale Avenue, London NW9 5HT, UK
a2 Food Hygiene Laboratory, Central Public Health Laboratory, 61 Colindale Avenue, London NW9 5HT, UK
a3 Communicable Disease Surveillance Centre, Public Health Laboratory Service, 61, Colindale Avenue, London NW9 5EQ, U.K.
a4 Unites des Enterobacteries, Institut Pasteur, 28 Rue du Docteur Roux, F-75724 Paris Cedex 15, France

Abstract

Molecular analyses based on plasmid profile typing and pulsed-field gel electrophoresis have defined a strain of Salmonella enterica serotype Anatum associated with the consumption of a particular brand of formula-dried milk responsible for an outbreak in late 1996/early 1997 involving 15 infants and 2 relatives in the UK, and 2 infants in France. The study has demonstrated the value of laboratory-based surveillance involving identification of the outbreak strain at the molecular level coupled with food microbiology and targeted epidemiological investigations, and has highlighted the importance of rapid communication and subsequent international collaboration through the European Union-funded Salm-Net salmonella surveillance network.

(Accepted May 8 1998)


Correspondence:
c1 Author for correspondence.
p1 Current address: Food Safety Authority of Ireland, Abbey Court, Lower Abbey Street, Dublin, Ireland.


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