Fetal and Maternal Medicine Review

Research Article

PRE-ECLAMPSIA AS A MARKER OF CARDIOVASCULAR DISEASE

LA MAGEEa1a2a3a4a5, J NEWSTEADa6, J NGa1, AM CÔTÉa7 and P VON DADELSZENa2a3a4a5

a1 Departments of Medicine, Vancouver, BC, Canada

a2 Obstetrics and Gynaecology, Vancouver, BC, Canada

a3 Health Care and Epidemiology, Vancouver, BC, Canada

a4 Child and Family Research Institute of British Columbia, University of British Columbia, Vancouver, BC, Canada

a5 British Columbia's Women's Hospital and Health Centre, Vancouver, BC, Canada

a6 Department of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada

a7 Department of Nephrology, University of Sherbrooke, Sherbrooke, Quebec, Canada.

Cardiovascular disease is the leading cause of death in women. The hypertensive disorders of pregnancy (HDP) are the most common medical complication of pregnancy, complicating up to 10% of pregnancies worldwide. They represent a leading cause of maternal mortality and morbidity in pregnancy. The most common of these disorders is gestational hypertension (5–6%). Using population-based data, approximately 1% of pregnancies are complicated by pre-existing hypertension, 5–6% by gestational hypertension without proteinuria, and 1–2% by pre-eclampsia.