Behavioral and Brain Sciences



Open Peer Commentary

Hallucinations and perceptual inference


Karl J. Friston a1
a1 Department of Imaging Neuroscience, Institute of Neurology, London WC1N 3BG, United Kingdom k.friston@fil.ion.ucl.ac.uk http://www.fil.ion.ucl.ac.uk

Abstract

This commentary takes a closer look at how “constructive models of subjective perception,” referred to by Collerton et al. (sect. 2), might contribute to the Perception and Attention Deficit (PAD) model. It focuses on the neuronal mechanisms that could mediate hallucinations, or false inference – in particular, the role of cholinergic systems in encoding uncertainty in the context of hierarchical Bayesian models of perceptual inference (Friston 2002b; Yu & Dayan 2002).